Defining Meta'omics

- the study of complex natural systems using molecular biology and/or mass spectrometric techniques aimed and analyzing a pool of biomolecules such as:

•DNA (Meta-Genomics)

•RNA (Meta-Transcriptomics)

•Proteins (Meta-Proteomics)

•Metabolites (Metabolomics) [targeted/untargeted]

•Lipids (Meta-Lipidomics)

•Sugars (Meta-Glycomics)


Hummel  et al.  (2011)

Hummel et al. (2011)

A comprehensive analysis of lipid molecules, “Lipidomics,” in the context of genomics and proteomics is crucial to understanding cellular physiology and pathology; consequently, lipid biology has become a major research target of the postgenomic revolution and systems
biology.
— Fahy et al. (2005) Journal of Lipid Research

Lipidomic Approach

  • Characterization of the dissolved and particulate lipid pool in culture, mesocosm experiments, and in situ.
  • High resolution accurate mass (HRAM) mass spectrometry paired with Ultra High Performance Liquid Chromatography.
  • Bioinformatic pipeline utilizing CAMERA and LOBSTAHS

Integrated Meta'omic

  • Meta-genomics and meta-transcriptomics utilized to better understand community composition and microbial metabolism of natural populations, as well as, test hypotheses from lipidomic results